Cellulose-based excipients are widely used in pharmaceutical and nutraceutical industries due to their unique physiochemical properties. Microcrystalline cellulose is commonly used as a diluent or binder. Additionally, powdered cellulose serves as a bulking agent and can also be used as a binder, disintegrant, or lubricant.

These excipients offer several benefits, including bio-compatibility, ease of manufacturing, and costeffectiveness, making them a popular choice for a wide range of pharmaceutical and nutraceutical formulations.

Microcrystalline Cellulose (MCC)

Microcrystalline Cellulose is a refined wood pulp, Finest element for tableting because of it’s purity. Used as an alternative to Carboxymethyl Cellulose and Lactose. Most commonly used in vitamin supplements & tablets.

101

  • Free flowing, ideal for wet granulation
  • For Wet granulation, extrusion, spherization.

102-102HD

  • Larger Size, For direct compression
  • Better Flow, improve flow properties of crystalline API’s, Proper disintegration

103

  • Low moisture content. Free flowing
  • For moisture sensitive API’s, Compatible with crystalline materials

105

  • Finest size
  • Direct compression of crystalline API’s, ideal for dry granulations, and wet granulations

112

  • Coarser particles, beneficial for direct compression, Lower in moisture content
  • Direct compression of high moisture sensitive drugs

113

  • Fine particle size, low moisture content
  • For better granulation of moisture sensitive drugs, roller compaction and dry granulation

200

  • Larger particle size, Better flow. good compressibility
  • Beneficial in weight variation drawback, thus improve content uniformity

301

  • High density particles
  • High Density, better flow, weight, uniformity, better capsule filling

Croscarmellose Sodium (CCS)

CCS, is a cross-linked polymer of Carboxy Methyl Cellulose and Sodium. It appears as white, fibrous, free-flowing powder. With Acrocell, tablet may disintegrate appropriately, ultimately providing good dissolution and actives absorption / desired bioavailability.

LM

  • Better disintegration
  • Ideal for low moisture sensitive drugs

Microcrystalline Cellulose Spheres (MCC Spheres)

MCC spheres are carriers for potential APls and nutraceuticals for targeted drug delivery system. They can be filled into capsules or compacted into tablets, while the tight article size distribution maximizes content uniformity.

MCC Spheres Products

  • MCC Spheres 100, MCC Spheres 200, MCC Spheres 350, MCC Spheres 500, MCC Spheres 700, MCC Spheres 1000

Characteristics

  • Spherical In Shape
  • 100 % Cellulose Spheres
  • Low Moisture
  • Feasible For Coating In FBP
  • High Surface Area
  • Uniform Coating Of API
  • Better Compressibility

 

Magnesium Stearate (MS)

MS acts as a lubricant, it provides a free flow to the blend throughout the manufacturing process. Thus speeding up production. It also prevents molecular clumping which ensures accurate dosage form.

Croscarmellose Sodium – LM

  • Better improvement of flow in moisture sensitive and crystalline API’s

Characteristics

  • High surface area
  • High whiteness
  • Better lubricity

 

Powdered Cellulose (PC)

Powdered Cellulose or Alpha Cellulose is a purified, mechanically disintegrated cellulose prepared from alpha-cellulose of fibrous plant materials. It is an odorless, tasteless, hydrophobic powder of various particle sizes, and forms - from flaky & coarse to fluffy & free flowing.

Powdered Cellulose Products

Characteristics

  • Tablet diluent and filler in two-piece
  • Hard capsules
  • A bulking agent
  • To increase the physical size of the dosage form
  • Acceptable compression properties
  • Reduce the sedimentation rate of oily suspension fills
  • Suspending agent in aqueous suspensions
  • Good for extrusion/spheronization

 

Microcrystalline Cellulose with Carboxy Methyl Cellulose (RC)

Desired viscosity modifier in suspensions as well as emulsions formulations

RC Products

Products

  • RC 581, RC 591

Characteristics

  • Viscosity Modifier
  • Stabilizer

 

Silicified Microcrystalline Cellulose (SMCC)

SMCC is a co-processed blend of Microcrystalline Cellulose (MCC) and Colloidal Silicon Dioxide (Si02) by spray drying technology. It brings better flowability to MCC's excellent compaction. It has dual characteristics of brittle fracture as well as plastic deformation; leading to superior binding properties. It can even replace granulations, while reducing no. of required excipients.

SMCC 90 LM

  • Low moisture content, better compressibility of low moisture sensitive drugs, direct compression

SMCC 90-HD90

  • Excellent compatibility
  • Desired flow properties
  • Good flow to direct compression APl’S
  • Increased production capacity
  • Easy for dry bledding in capsule
  • Improved blending properties

SMCC 50 LD

  • Low density
  • Better for low-dose drug formulation
  • Flow improvement of crystalline blends

SMCC 50

  • High intrinsic flow
  • Enhanced lubrication efficiency
  • Superior binding properties
  • Enhance blending efficiency
  • Ideal for capsule manufacturing
  • Improved properties like weight uniformity, friability, disintegration, etc.